How To Close Itunes App On Mac

You had your iPod plugged into your computer before you opened iTunes. If that’s the case, simply unplug your iPod from your computer, close iTunes (iTunes may close on its own after you unplug your iPod if it is open but not responding) and open it up again. This is what fixed my issue. Part 3: Delete Apps Downloaded from Mac App Store. One of the best alternative to delete any app is by simply deleting it from the sales page from the App Store. Once you have done that, you will no longer be able to download it form there anymore. But, the app will remain active in the iTunes account which is associated with that.

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Last fall’s release of iTunes 12.7 disappointed a lot of people with the abruptness of change.The most notable one was removing the ability for iTunes to handle backing up iOS apps and syncing.
To “close” programs (also called applications or apps) you simply quit them. Or, the keyboard shortcut Command+Q. The term “close” is used both to talk about windows (close a window) and apps (close or quit an app). So just quit the apps you aren’t using.

To quit (close) a Mac app normally, choose Quit from the app's menu in the menu bar, or press Command (⌘)-Q. If the app doesn't quit, follow these steps to force the app to quit.

How to force an app to quit

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Press these three keys together: Option, Command, and Esc (Escape). Or choose Force Quit from the Apple menu  in the upper-left corner of your screen. (This is similar to pressing Control-Alt-Delete on a PC.)

Then select the app in the Force Quit window and click Force Quit.

You can even force the Finder to quit, if it stops responding: Select Finder in the Force Quit window, then click Relaunch.

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How to force an app to close on your iPhone, iPad, or iPod touch.

There are various reasons this happens. In a nutshell, something on your system is still 'hooked' to iTunes, so it can't close.
Are you using any iTunes plugins?
If not, then the other most liekly cause is antivirus software that is not letting iTunes save the library file when it closes.
Other people have had good luck uninstalling the Apple Mobile Device Manager from Start > Control Panel > Add/Remove programs.
That program is only needed if you have an iTouch or iPhone:
http://docs.info.apple.com/article.html?artnum=302488